ncRNA name | GPR91 shRNA |
ncRNA Category | shRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | shRNA knockdown, H&E staining, immunofluorescence, qPCR, Western blot |
Expression pattern | associated |
Functional description | The retinal telangiectatic vessels, basement membrane thickness, and Evans blue dye permeability were attenuated by treatment with GPR91 shRNA. |
PubMed ID | 25324681 |
Year | 2014 |
Title | ERK1/2/COX-2/PGE2 signaling pathway mediates GPR91-dependent VEGF release in streptozotocin-induced diabetes. |
Drug-related ncRNA | NA |
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